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Assessing Bioequivalence of Generic Antiepilepsy Drugs Ann Neurol 70:221-228,192, Krauss, G.L.,et al, 2011 See this aricle in Pubmed Article Abstract Most generic AED products provide total drug delivery (AUC) similar to reference products; differences in peak concentrations between formulations are more common. Switches between generic AED products may cause greater changes in plasma drug concentrations than generic substitutions of reference products.

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